معرفی
Professor Filippo Menolascina holds a Personal Chair of Engineering Biology at the University of Edinburgh's School of Engineering, affiliated with the Centre for Engineering Biology and Institute of Bioengineering. His research bridges engineering principles with biological systems to advance synthetic biology and biomolecular network design.
Menolascina's research focuses on engineering biology, gene regulatory networks, and cybergenetic control systems. He develops computational models for biomolecular circuit calibration, synthetic promoter design in mammalian cells, and bacterial chemotaxis mechanisms. His work integrates control theory with synthetic biology to create programmable biological systems for medical applications.
Recent publications (2021-2023) reveal a strong trend in cybergenetic control of biomolecular networks, split intein engineering for logic gates, and in vitro disease modeling. Key themes include computational design of genetic circuits, trade-offs in biological sensing systems, and multimodal databases for metabolic liver disease, demonstrating cross-disciplinary applications from fundamental microbiology to clinical hepatology.
Scientific awards: No specific awards mentioned in source material.
Menolascina has secured significant research funding as Principal Investigator for:
- Biodynamic Atlas (Department for Science, Innovation & Technology, 2024)
- McSynC: in vivo automatic Model calibration of Synthetic Circuits components (EPSRC, 2018-2020)
- 21EBTA Engineering Biology for Cell and Gene Therapy Applications (BBSRC, 2022-2024)
- Fostering Synthetic Biology standardisation (EU, 2018-2021)
He leads interdisciplinary teams within the Centre for Engineering Biology, collaborating with medical researchers on liver disease models and engineers on respiratory droplet dispersion studies. His lab develops computational tools for synthetic circuit design while maintaining strong industry and international academic partnerships in bioengineering standardization.
