Ferdinando Mannello

Ferdinando Mannello is a Full Professor of Clinical Biochemistry at the University of Urbino Carlo Bo and serves as the Coordinator of the Doctoral School in Biomolecular and Health Sciences. He also acts as Dean of the School of Biological Sciences and Director of the Laboratory Unit of Clinical Biochemistry, focusing on translational research in vascular pathologies and chronic diseases.

• Current Institution: University of Urbino Carlo Bo
• Department: Biomolecular Sciences (DISB)
• Academic Role: Full Professor

His research integrates clinical biochemistry with molecular biology, emphasizing:

• Biochemical mechanisms of thromboinflammation
• Role of matrix metalloproteinases (MMPs) in disease progression
• Development of circulating biomarkers for early diagnosis
• Impact of oxidative stress and redox homeostasis
• Pharmacological modulation of inflammatory pathways
• Translational applications in vascular and metabolic diseases

Recent publications highlight his leadership in:

• Identifying histone-mediated thromboinflammatory pathways
• Characterizing MMP/TIMP balance in chronic wounds
• Exploring metal-induced carcinogenic mechanisms
• Advancing biomarker discovery for venous disorders
• Developing novel antithrombotic strategies
• Integrating omics approaches in translational medicine

Scientific Awards:

• Breast Cancer Research Foundation Awards (2005-2011)

Collaborations span institutions including Sapienza University of Rome, Imperial College London, and medical centers in Finland and the U.S., with significant contributions to understanding disease mechanisms through proteomics and metabolomics.