معرفی
Dr. Fadila Bouamr is a Senior Staff Scientist at the Laboratory of Molecular Microbiology, part of the National Institute of Allergy and Infectious Diseases (NIAID). Her research focuses on the molecular mechanisms of HIV-1 and retroviral assembly/egress, particularly ESCRT machinery recruitment and ubiquitin's role in virus release.
- Education:
- Ph.D., Victor Segalen Bordeaux University (1997)
- Postdoctoral training: SUNY Stony Brook (Carol Carter lab), Columbia University (Steve Goff lab)
- Research Themes:
- Viral particle assembly and budding
- ESCRT pathway's role in membrane scission
- Host factor screening for virus release
- Structure-function studies of viral proteins
- Ubiquitin-mediated viral egress
- Virus-host interplay in cytokinesis
- Recent Publication Trends:
- 2024 studies on ESCRT-I helical scaffolding
- 2021 work on TRIM5α's protease-targeting mechanism
- 2020 structural analysis of Alix-ESCRT interactions
- 2019 discovery of TRIM5α's flavivirus restriction
- 2018 investigation of mannose receptor's HIV-1 inhibition
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