معرفی
Dr. Fadhel Shaheen is a cancer biology researcher at Newcastle University, UK. Holding the rank of Research Fellow, he has produced a focused body of work centered on androgen receptor biology and DNA damage response pathways in prostate and ovarian cancers. His collaborative studies with senior investigators such as Prof. Ruth Plummer and Prof. Craig Robson have explored therapeutic vulnerabilities in cancer cells.
Research Interests:
- Androgen receptor (AR) signaling and transcriptional regulation
- Epigenetic modifications of AR, including methylation by SET9
- DNA double-strand break repair mechanisms as therapeutic targets
- Apoptotic pathways modulated by MDM2 inhibitors (e.g., Nutlin-3)
- Biomarker discovery for hormone sensitivity in ovarian cancer
Scientific Awards:
No awards explicitly listed in the provided text.
Collaborations & Funding:
Dr. Shaheen has co-authored multi-institutional studies involving Newcastle University investigators (Drs. Ian Logan, Urszula McClurg, Dominic Jones, Luke Gaughan, Stuart McCracken, Kelly Coffey, Pawel Znojek, Ann Fisher) and external partners, suggesting active grant funding and collaborative networks.
Laboratory & Teams:
While specific laboratory names are not provided, the co-authorship patterns indicate affiliation with cancer biology and translational research teams at Newcastle University, likely within the Faculty of Medical Sciences or associated cancer research institutes.