معرفی
Professor Evan Reid is a Professor of Neurogenetics and Molecular Neurobiology at the Cambridge Institute for Medical Research (CIMR), University of Cambridge, where he serves as a Principal Investigator. Affiliated with St Edmund's College, his research focuses on unraveling the molecular pathology of axon death in hereditary spastic paraplegias (HSPs), with particular emphasis on spastin protein function and neuronal trafficking mechanisms.
His research interests center on neurogenetics and molecular neurobiology, specifically investigating how mutations in HSP genes disrupt organelle biology and membrane trafficking in neurons. The Reid Lab employs cutting-edge approaches including human iPSC-derived neurons, advanced microscopy, and genome sequencing to understand axonal degeneration mechanisms and identify therapeutic targets for HSPs and related neurological conditions.
Analysis of his 15 most recent publications reveals a strong focus on lysosomal function, endosomal dynamics, and mitochondrial pathology in neurodegenerative disorders. His work frequently bridges rare disease genetics with fundamental cell biological processes, demonstrating how defects in organelle trafficking contribute to motor neuron disease.
His research group includes Sam Cheers, Isabelle Hall, Rowan John, Aishwarya Nadadhur, and Bart Nieuwenhuis. Funding for his laboratory comes from the Medical Research Council, Tom Wahlig Stiftung, and NIHR Cambridge Biomedical Research Centre.
