معرفی
Dr. Euan W. Baxter is a Research Fellow at the School of Medicine, University of Leeds, Faculty of Medicine and Health. He has held research positions at the University of Edinburgh, University of Glasgow, Fred Hutchinson Cancer Research Center, and the University of York. His current work focuses on the molecular biology of Fc gamma receptors and gene regulation.
Education:
- PhD, Medical School, University of Edinburgh
- BSc (Hons)
Dr. Baxter's research centers on gene regulation, chromatin structure, and immune signaling. He has developed and applied advanced techniques including Chromatin Immunoprecipitation (ChIP), DNaseI hypersensitive site mapping, siRNA knockdown, and bioluminescent fusion protein systems. His work spans cancer biology (medulloblastoma, bladder cancer, thymic lymphoma) and immunology (Fc receptors, SERPINs, macrophage differentiation). He has extensive experience in molecular cloning, stable cell line generation, and cellular assay development.
His recent publications reflect a strong trend in immune receptor signaling, protein engineering, and cancer-related gene regulation. Key themes include the development of luciferase-based reporters for real-time signaling, specificity profiling of Affimer proteins, and the role of p53 regulators in oncogene addiction. These works integrate molecular biology, immunology, and translational cancer research.
Scientific Awards:
- No awards listed in the provided text.
Dr. Baxter has contributed to several research grants and collaborative projects, particularly in cancer and immunology. He has mentored students and is involved in postgraduate research opportunities in the Discovery and Translational Science group. While no direct supervision list is provided, his lab work supports PhD and post-doctoral training. He has developed novel assays for apoptosis, receptor signaling, and gene expression analysis.
He is actively involved in the Discovery and Translational Science research group at the University of Leeds, where he leads experimental work on Fc gamma receptor biology. His lab utilizes HEK293 and THP-1 cell lines, develops recombinant proteins, and applies flow cytometry and molecular cloning techniques. The team focuses on understanding immune signaling mechanisms and developing tools for therapeutic targeting.
