Eshwari Dathathri

Eshwari Dathathri serves as a Researcher at the Biomedical and Environmental Sensorsystems group within the MESA+ Institute at the University of Twente, focusing on translational cancer diagnostics with emphasis on prostate malignancies and liquid biopsy technologies.

Her core research domains include:

• Circulating Tumor Cell (CTC) isolation and characterization (76% fingerprint relevance)
• Neoplasm biomarker discovery for metastatic prostate cancer
• Drug delivery systems utilizing chitosan and polyvinyl alcohol matrices
• Swelling dynamics in pharmaceutical formulations
• Cancer-associated fibroblast profiling in castration-naïve disease

Analysis of her 2022-2025 publications reveals consistent innovation in CTC enrichment techniques, secretome profiling, and extracellular vesicle analysis. Her work bridges biomedical engineering and clinical oncology, developing immunomagnetic separation methods from leukapheresis products while identifying novel biomarkers like cell cycle-dependent PSA secretion. Key trends show progression from basic drug delivery mechanisms toward clinical validation of diagnostic tools for treatment monitoring.

Dathathri operates within the MESA+ Institute's interdisciplinary ecosystem, collaborating with clinical partners including Institut Curie (Paris) and Netherlands Cancer Institute. Her research leverages advanced sensor technologies for environmental and biomedical applications, with recent work focusing on functional characterization of circulating cancer-associated fibroblasts as potential therapeutic targets.