Esben Trabjerg

Esben Trabjerg serves as an Assistant Professor in the Protein Analysis Group within the Department of Pharmacy at the University of Copenhagen's Faculty of Health and Medical Sciences. His research focuses on developing structural mass spectrometry methods to investigate protein conformational dynamics, particularly hydrogen-deuterium exchange mass spectrometry (HDX-MS) and cross-linking mass spectrometry (XL-MS).

His primary research areas include protein higher-order structure analysis by LC-MS/MS, protein-protein interaction site identification, epitope mapping of antibodies, and therapeutic protein processing. Trabjerg's biological focus centers on the interaction between peptide-antigen loaded major histocompatibility complex (pMHC) and T-cell receptors (TCR), which is critical for immune system function. His publication record shows consistent output in high-impact journals spanning structural biology, immunology, and analytical chemistry, with emphasis on method development and biological applications.

Notable collaborations include work with Rand K.D., Andersen J.T., and Leitner A. across multiple publications. His research demonstrates strong integration of experimental mass spectrometry with biological problem-solving, particularly in immune system protein interactions and biopharmaceutical analysis.