Eric Pearlman

Eric Pearlman is a Professor at the University of California, Irvine (UCI) School of Medicine, affiliated with the Departments of Physiology & Biophysics and Ophthalmology & Visual Sciences. He serves as Director of the Institute for Immunology.

Research Focus:

Dr. Pearlman investigates immune responses in ocular onchocerciasis (river blindness), emphasizing the role of Wolbachia bacteria and Toll-like receptor 4 (TLR4) in pathogenesis. His work spans immunology, parasitology, and ophthalmology.

Scientific Contributions:

Key publications include studies on:

• Wolbachia-Onchocerca volvulus interactions (2002)
• TLR4/MyD88 signaling in keratitis (2006)
• Multi-epitope vaccine design (2019)