Eric J. Strobel

Eric J. Strobel is an Assistant Professor in the Department of Biological Sciences at the University at Buffalo (UB), within the College of Arts and Sciences. He holds the title of UB Exceptional Scholar and has received the Young Investigator Award. His research focuses on understanding how RNA molecules fold during transcription and how this process influences gene regulation and RNA biogenesis. Strobel's work combines experimental and computational approaches to study cotranscriptional RNA structure and function.

Education:

• BS, St. John’s University
• PhD, Cornell University
• Postdoctoral Research: Northwestern University and Cornell University

Research Interests:

Strobel investigates the interplay between RNA sequence, structure, and function during transcription. His lab develops high-throughput methods to analyze nascent RNA folding, including chemical roadblocking and magnetic bead-based purification techniques. Key areas include cotranscriptional RNA folding dynamics, riboswitch regulation, and the impact of structural constraints on RNA function. His work bridges fundamental biology with applications in synthetic biology and disease understanding.

Publications:

Strobel's recent work explores coordinated cotranscriptional folding events, transcription elongation complex purification, and RNA structure prediction. His studies highlight mechanisms underlying riboswitch function, transcriptional pausing, and the development of novel genomic tools.

Awards:

• UB Exceptional Scholar
• Young Investigator Award

Advising & Grants:

While specific grants are not detailed here, Strobel's research is supported by methodological innovations in RNA biology. His lab focuses on training students in interdisciplinary approaches combining biochemistry, genomics, and computational biology.

Labs/Teams:

Strobel leads the RNA Dynamics Laboratory at UB, specializing in cutting-edge techniques for studying RNA structure-function relationships during transcription.