Eric J. Moore

Dr. Eric J. Moore is a Professor of Otolaryngology and serves as the Chair of the Department of Otolaryngology-Head and Neck Surgery at Mayo Clinic. He holds multiple consultative appointments across the institution, including in the Division of Oral Diagnosis and Oral and Maxillofacial Surgery (Department of Surgery), Department of Neurosurgery, and Department of Pediatric and Adolescent Medicine. As a leading head and neck cancer surgeon and facial plastic and reconstructive surgeon, Dr. Moore specializes in complex tumor removal and reconstructive surgery.

Dr. Moore's research focuses on improving patient outcomes through innovative surgical techniques and treatment strategies. His primary research areas include parotid gland surgery, transoral robotic surgery (where he assisted in the original FDA approval process), deintensification strategies for HPV-related oropharyngeal cancer, and microvascular reconstruction using computer modeling and 3D printing technology. His research aims to minimize incisions, maintain normal tissue, and improve reconstructions to restore patients' appearance and function after cancer surgery.

His publication record demonstrates consistent scholarly output with 218 publications spanning from 1999 to 2025, with recent focus on HPV-related oropharyngeal cancer, liquid biopsy techniques, and surgical innovations. Analysis of his recent publications shows a strong emphasis on translational research that bridges laboratory findings with clinical applications, particularly in the areas of precision oncology and surgical innovation.

• Castle Connolly Top Doctors (2011-2021)
• Distinguished Clinician Award (2012)
• Gunnar Holmgren Award (2021)
• Joseph H. Ogura Memorial Lecturer Award (2017)
• Academy of Educational Excellence Fellow (2020)
• Multiple Teacher of the Year awards
• Distinguished Humanitarian Award (2007)

As an educator, Dr. Moore provides mentorship to residents and fellows, with numerous teaching awards recognizing his excellence in medical education. His humanitarian work includes leading and participating in surgical missions worldwide. His clinical practice focuses on head and neck cancer treatment with particular expertise in robotic surgery, microvascular reconstruction, and treatment of HPV-related cancers with minimal morbidity.

Dr. Moore's laboratory and clinical research activities are centered at the Mayo Clinic Comprehensive Cancer Center and the Head and Neck Cancer Center, where he leads research efforts to improve surgical outcomes and develop innovative treatment approaches for head and neck cancer patients.