معرفی
Engin Deniz, MD, is an Associate Professor of Pediatrics (Critical Care) at Yale School of Medicine, Yale University. He serves in the Department of Pediatrics and leads the Deniz Lab, with affiliations to the Khokha Lab and Pediatric Critical Care Transport Program. His clinical practice focuses on the Pediatric Intensive Care Unit at Yale New Haven Children’s Hospital.
Education
- Fellowship: Yale University School of Medicine (2012)
- Residency: Cohen Children's Medical Center of New York (2009)
- Residency: Long Island College Hospital Beth Israel Medical Center (2007)
- MD: University of Istanbul (2002)
Research Focus
Dr. Deniz's research centers on genetic mechanisms underlying congenital disorders, particularly hydrocephalus, ciliopathies, and congenital heart defects. His work integrates molecular genetics with developmental biology to explore neural progenitor dysfunction, cerebrospinal fluid dynamics, and cilia-related pathologies. Current investigations focus on epigenetic dysregulation in hydrocephalus and ciliary stability in heterotaxy syndromes.
His publications demonstrate strong interdisciplinary approaches combining Xenopus models, optical coherence tomography, and genomic analyses to elucidate pediatric disease mechanisms.
Honors & Awards
- The Mae Gailani Junior Faculty Award (Yale School of Medicine, 2024)
- Innovator Award (Hydrocephalus Association, 2019)
Clinical & Academic Roles
As Sub-Investigator for the Pediatric Genomics Discovery Program, Dr. Deniz contributes to genetic diagnosis initiatives. His clinical approach emphasizes family-centered care in critical care settings, with particular attention to congenital abnormalities and life-threatening pediatric conditions.
Laboratory & Collaborations
The Deniz Lab focuses on modeling congenital disorders using Xenopus tropicalis, investigating CSF dynamics, ciliary function, and neural development. Key collaborators include Mustafa Khokha and Kristopher Kahle, with research spanning molecular medicine, pharmacology, and physiology.