معرفی
Dr. Ellen Gould Chadwick serves as Professor of Pediatrics at Northwestern University's Feinberg School of Medicine and Director of the Section of Pediatric, Adolescent and Maternal HIV Infection at Ann & Robert H. Lurie Children's Hospital of Chicago. As an attending physician in Pediatric Infectious Diseases since joining Northwestern in 1985, she leads clinical care for HIV-affected pediatric populations and directs the Illinois Perinatal HIV Hotline providing 24/7 consultation for obstetric and pediatric providers.
Education:
- BA: Denison University (1975)
- MD: University of Virginia (1979)
- Residency: Northwestern University, McGaw Medical Center (Children’s Memorial Hospital), Pediatrics (1982)
- Fellowship: Northwestern University, McGaw Medical Center (Children’s Memorial Hospital), Pediatrics Infectious Diseases (1985)
Dr. Chadwick's research centers on Pediatric HIV/AIDS with pioneering work in antiretroviral therapy optimization, prevention of mother-to-child transmission, and long-term health outcomes in perinatally infected youth. Her leadership in the NIH-funded IMPAACT network focuses on pharmacokinetics, pharmacogenomics, and intensive early therapy for HIV remission in infants, while her co-PI role in the Pediatric HIV/AIDS Cohort Study (PHACS) tracks longitudinal effects in over 4,000 mother-infant pairs and young adults. She integrates clinical care with global health initiatives through physician training in African nations.
Recent publications reveal critical trends in bone health deterioration among HIV-positive youth, nutritional biomarkers affecting pregnancy outcomes, safety profiles of novel antiretrovirals like bictegravir during gestation, and substance use patterns in perinatally infected adolescents. These studies collectively advance precision medicine approaches across HIV care continua from prenatal exposure to young adulthood.
Scientific Awards:
- Susan B. DePree Founders' Board Professor in Pediatric Adolescent and Maternal HIV Infection (2019)
- Doctor of Humane Letters, Denison University (2012)
Dr. Chadwick directs major NIH-funded initiatives including PHACS and IMPAACT protocols while serving on the U.S. Department of Health and Human Services Panel on Pediatric HIV Therapy. Her $25M+ grant portfolio supports multicenter trials across 50+ international sites, with recent awards focusing on HIV cure strategies and adolescent transition care. She mentors junior investigators through the Pediatric Infectious Diseases Society and has trained over 200 physicians in resource-limited settings.
She leads the PHACS Operations Center and IMPAACT pharmacology core, directs Northwestern's Pediatric HIV Program serving 500+ patients annually, and chairs the Cure Research Agenda Committee developing novel remission strategies. Her team operates the Illinois Perinatal HIV Hotline and collaborates with the Third Coast Center for AIDS Research integrating epidemiology, virology, and behavioral science.
