معرفی
Dr. Ella Atlas is an Adjunct Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa, affiliated with the Faculty of Medicine. She serves as a Research Scientist at Health Canada, focusing on environmental pollutants' impacts on human health. Her work bridges academic research and public health policy.
- Academic Rank: Adjunct Professor
- Institution: University of Ottawa & Health Canada
- Department: Biochemistry, Microbiology and Immunology
Research Interests
- Chemically induced obesity (obesogens)
- Chemically induced carcinogenesis
- In vitro models for toxicity testing
- Transcriptional regulation
- Nuclear receptor interactions
Her recent publications emphasize transcriptomic analyses of environmental chemicals like bisphenols and PFAS. Using 3D cell models (hepatocytes, mammary epithelial cells), her work explores how these substances disrupt metabolic processes and induce carcinogenic changes. Collaborative efforts include the HumanIslets.com Consortium, which focuses on diabetes-related islet data integration.
Methodological Innovations
- 3D human liver spheroids for toxicity studies
- High-throughput transcriptomic screening
- Adverse outcome pathway (AOP) modeling
- In vitro adipogenesis assays
Key Research Themes
- Environmental pollutants as drivers of metabolic disorders
- Chemical carcinogenicity in mammary glands
- Development of predictive toxicity models
- Public health implications of endocrine disruptors
