
معرفی
Elizabeth A. Jacobsen, Ph.D., is an Assistant Professor at Mayo Clinic in Phoenix, Arizona, with appointments in the Department of Biochemistry and Molecular Biology, Department of Immunology, and as Associate Professor of Medicine. She is based in the Division of Allergy, Asthma, and Clinical Immunology within the Department of Internal Medicine.
Education:
- Ph.D. in Molecular and Cellular Biology, Arizona State University
- Postdoctoral Fellowship, Laboratory of Dr. Jiping He, Arizona State University
- Postdoctoral Fellowship, Laboratory of Dr. James J. Lee, Mayo Clinic
Research Interests:
Dr. Jacobsen is a leading researcher in eosinophil immunobiology, focusing on the dual roles of eosinophils in health and disease. Her work explores how eosinophils are differentially activated and interact with other immune cells such as T cells, dendritic cells, and group 2 innate lymphoid cells. She investigates their contributions to allergic asthma, lung transplantation, chronic rhinosinusitis, and metabolic conditions like obesity. A key aspect of her research is identifying eosinophil subtypes and their functional roles beyond traditional type 2 inflammation.
Recent Research Trends:
Her recent publications (2024) highlight a multidisciplinary approach, spanning lung development, surgical transplantation models, biomarker validation, and immunometabolism. These studies emphasize eosinophils as both effectors and regulators in immune responses, with translational applications in diagnostics and therapeutic targeting.
Scientific Awards:
No specific awards were mentioned in the provided text.
Advising and Grants:
While no formal students are listed, Dr. Jacobsen leads and co-leads significant NIH-funded research projects. She is Principal Investigator (PI) on grants from NIAID and NHLBI, including studies on ozone-exposed pollen responses and eosinophil subtyping in biopsies. She also serves as Co-PI on projects related to asthma diagnostics and perioperative outcomes, demonstrating strong collaborative and independent research leadership.
Labs and Teams:
Dr. Jacobsen conducts her research at Mayo Clinic in Phoenix, collaborating with experts in lung transplantation, allergy, and immunology. Her work is integrated within multidisciplinary teams focusing on inflammation, transplantation immunology, and clinical biomarker development.
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