Edward Machtinger

Edward Machtinger, MD, is Professor of Medicine at the University of California, San Francisco (UCSF), School of Medicine. He serves as Director of the Women’s HIV Program (WHP) and Director of the Center to Advance Trauma-informed Health Care (CTHC), playing a pivotal role in advancing trauma-informed models in primary care.

• University: University of California, San Francisco
• School: School of Medicine
• Position: Professor of Medicine
• Email: edward.machtinger@ucsf.edu

Dr. Machtinger’s research centers on trauma-informed care, adverse childhood experiences (ACEs), HIV, and health disparities, particularly among women and underserved populations. His work aims to integrate mental health and substance use services into primary care and to address the root causes of illness through trauma-informed approaches. He has published extensively on the links between trauma and HIV outcomes, interventions for trauma and co-occurring disorders, and systemic implementation of trauma screening.

His recent publications highlight a shift toward holistic, healing-centered models in healthcare, with a focus on ACEs screening, clinic readiness, and protective factors in primary care. The articles span topics in HIV, trauma, behavioral health, and public health policy, reflecting an interdisciplinary and translational research agenda.

• UCSF School of Medicine 2013 Osler Distinguished Teaching Award

Dr. Machtinger is a principal or co-principal investigator on multiple major grants, including initiatives funded by the California Department of Health Care Services, Genentech, HRSA, and SAMHSA. He co-leads the UCLA/UCSF ACEs Aware Family Resilience Network (UCAAN) and led the California ACEs Learning and Quality Improvement Collaborative (CALQIC). He has secured over $100 million in grant funding since 2018 and advises national and state-level policy bodies on trauma, HIV, and behavioral health integration. He mentors junior researchers and clinicians and is actively involved in teaching and curriculum development.

He is affiliated with several key UCSF entities, including the AIDS Research Institute (ARI), and serves on executive committees overseeing Ryan White funding and California’s opioid response. His work bridges clinical practice, research, policy, and community engagement.