Edgar Pena

Edgar Pena serves as an Assistant Professor in the Department of Biomedical Engineering at the University of Minnesota, specializing in computational neuroengineering and neuromodulation techniques. His work bridges biomedical signal processing with clinical applications for neurological disorders.

His primary research focuses on computational modeling of nerve stimulation, energy-efficient neuromodulation, and individualized neural interface design. Key investigations include kilohertz-frequency nerve block mechanisms, deep brain stimulation optimization, and vagus nerve stimulation for cardiovascular applications. His fingerprint analysis reveals strong expertise in Deep Brain Stimulation (100%), Nerve Block (50%), and Computational Modeling (38%), with emerging work in Parkinson's disease biomarkers.

Recent publications demonstrate consistent focus on nerve block efficiency and stimulation parameter optimization across 10 research outputs since 2016. His work shows increasing emphasis on clinical translation, particularly in cardiovascular neuromodulation (2023-2024) and Parkinson's disease treatment personalization (2021).

As Principal Investigator, Dr. Pena leads an active American Heart Association grant (2025-2028) titled Neural Recordings to Improve Selectivity of Vagus Nerve Stimulation for Cardiovascular Modulation, collaborating with S. Ikramuddin, H.H. Lim, and J. Osborn. His research leverages computational models to enhance therapeutic precision in neural interfaces while minimizing side effects like onset responses.