Eain Cornford

Eain Cornford is a Professor in the Department of Neurology at the University of California, Los Angeles (UCLA) and a Member of the Brain Research Institute. Based at the Healthcare Sys Bldg. in Los Angeles, CA, his work bridges fundamental neuroscience and clinical applications with contact via cornford@ucla.edu and 310-268-4426.

Dr. Cornford's research centers on brain metabolism and blood-brain barrier (BBB) function, with seminal contributions to understanding glucose transporter modulations—particularly the Glut1 isoform in brain tumors. His laboratory employs quantitative electron microscopy, in vivo brain uptake measurements, internal carotid artery perfusion analyses, and cerebral blood flow rate quantification to correlate physiological transport with subcellular protein localization. A secondary focus explores gender-specific transport and metabolism in schistosome parasites, demonstrating interdisciplinary reach across neurology and parasitology.

Analysis of his 2002-2024 publications reveals three dominant trajectories: (1) BBB mechanisms and drug delivery systems, (2) neurological manifestations of systemic diseases (e.g., narcolepsy, parasitic infections), and (3) rare neurosurgical case reports. His work consistently merges molecular techniques with clinical observations, exemplified by studies on hypocretin system alterations in sleep disorders and cerebral complications of Chagas disease. This integrative approach has established him as a key contributor to translational neurovascular research.

Dr. Cornford leads an active laboratory investigating subcellular BBB regulation, with recent work emphasizing non-invasive drug delivery methods and tumor metabolism. His collaborations span neurosurgery, infectious disease, and endocrinology departments, reflecting the cross-disciplinary nature of modern neuroscience research at UCLA.