Douglas Shepherd

Douglas Shepherd is an Associate Professor of Physics at Arizona State University (ASU), affiliated with the School of Life Sciences and the Center for Biological Physics. He leads the Quantitative Imaging and Inference (QI2) Lab, which focuses on developing high-throughput fluorescence imaging methods and statistical tools to study cellular organization in tissues and organs. His research contributes to the Chan Zuckerberg Initiative's Human Cell Atlas, particularly in mapping gene expression in the human lung.

Education:

• Ph.D. in Physics, Colorado State University (2011)
• B.S. in Physics, University of California Santa Barbara (2003)

Research interests span bioimaging, gene regulation in pathogenic bacteria, optical device development, and the physics of biological systems. The QI2 Lab emphasizes open science, sharing software and datasets for microscopy control and analysis via platforms like GitHub. Recruitment is ongoing for postdocs and students in theoretical/experimental roles.

The lab’s work integrates advanced microscopy with computational modeling to address questions in tissue development and cellular decision-making. Recent technical innovations include structured illumination modules and light-sheet microscopy platforms for high-resolution imaging.