Douglas Koshland

Douglas Koshland is a Professor in the Department of Molecular & Cell Biology at the University of California, Berkeley. He also holds the Richard and Rhoda Goldman Distinguished Chair in the Biological Sciences.

• Research focus: Fundamental cell biology processes using budding yeast
• Key areas: Higher-order chromosome structure, genome integrity, desiccation tolerance

Research Interests

The Koshland laboratory explores unsolved mysteries in cell biology through genetic, biochemical, and imaging studies. Their work addresses:

• Molecular mechanisms of chromosome structure via SMC complexes
• Genome integrity maintenance and DNA repair
• Stress tolerance through desiccation studies with biomedical applications

Scientific Recognition

• Elected Member of the National Academy of Sciences

Methodological Innovation

Develops novel genetic reagents and in vitro assays to dissect molecular mechanisms of chromosome biology. Research reveals principles applicable to all eukaryotes, including insights into human diseases and drought tolerance.