معرفی
Domenico Praticò, MD, FCPP is a Professor in the Department of Neural Sciences at Lewis Katz School of Medicine, Temple University, and the Founding Director of the Alzheimer's Center at Temple. His research focuses on clinical pharmacology, oxidative biology, and neurodegeneration.
- MD, University of Rome "La Sapienza" (1986)
- Internship, Residency, and Fellowship at University of Rome "La Sapienza"
- Cardiovascular Science Fellowship, University of Dublin (1994)
Dr. Praticò investigates the role of bioactive oxidized lipids, oxidative stress, and neuroinflammation in aging, Alzheimer's disease, and cardiovascular disorders. His lab employs cellular and animal models to translate findings into human disease understanding.
Recent publications highlight his work on Alzheimer's disease mechanisms involving non-coding RNAs, endosomal trafficking, lipid metabolism, autophagy, and vascular contributions. His studies bridge neurobiology, cardiovascular research, and translational medicine.
- Fellow of the Center for Clinical Pharmacology (FCPP)
His lab integrates in vitro systems and transgenic mouse models to study APP processing, Aβ metabolism, tau pathology, and synaptic dysfunction. The Pratico Lab emphasizes drug discovery for neurotherapeutics and biomarker identification.
