Kevin Williams

Kevin Williams, MD is a Professor in the Department of Cardiovascular Sciences at the Lewis Katz School of Medicine, Temple University, with secondary appointments in Medical Genetics and Molecular Biochemistry. He directs research at the Aging + Cardiovascular Discovery Center and serves as principal investigator for multiple NIH-funded projects.

His educational credentials include:

• MD from Johns Hopkins University (1980)
• Internal Medicine Residency at University of Chicago Medical Center (1983)
• Clinical Endocrinology Fellowship at Yale-New Haven Hospital (1984)
• Metabolism Fellowship at Columbia University (1985)

Dr. Williams' research revolutionized understanding of atherosclerosis through his work on LDL retention in arterial walls, establishing foundational links between basic science and clinical approaches. His laboratory investigates diabetic dyslipidemia mechanisms and insulin-signaling proteins, emphasizing that atherosclerosis causes 50% of Western deaths and 80% of diabetic cardiovascular events. Current work addresses lipid metabolism in autoimmune diseases and cancer.

His 2025 publications reveal intensified focus on cardiovascular risk in lupus/dermatomyositis patients, lipid dysregulation in obesity/cancer, and novel therapeutic targets like SCD inhibition. The work spans molecular mechanisms to clinical management, with strong emphasis on translational applications for high-risk populations.

Dr. Williams serves as Consulting Editor for the Journal of Clinical Investigation and on editorial boards for Arteriosclerosis, Thrombosis and Vascular Biology and Rambam Medical Journal. He holds 11 patents related to lipoprotein modification and diabetic dyslipidemia treatment.

His laboratory at Temple investigates corrective strategies for postprandial lipid disposal defects in diabetes and explores membrane lipid remodeling in metabolic disease. Current NIH projects focus on early atherosclerotic disease intervention and lipid-based therapeutic approaches for high-risk cardiovascular patients.