معرفی
Ditte Hededam Welner is a Senior Researcher & Group Leader at the Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark. Her research focuses on Enzyme Engineering and Structural Biology, particularly the development of enzyme biocatalysts for sustainable industrial production of natural products like aromas, dyes, and pharmaceuticals. She leads efforts to replace petroleum-based chemical synthesis with eco-friendly bio-based processes, emphasizing glycosyltransferase (GT) engineering to enhance substrate specificity, efficiency, and stability.
Education: Biochemistry, University of Copenhagen (2000–2011).
Research Interests: Glycosylation mechanisms, high-throughput enzyme discovery/evolution, structural biology techniques (X-ray crystallography, NMR), and biocatalysis applications in sustainable chemistry. Her work contributes to UN SDG 9 (Industry, Innovation, and Infrastructure) and SDG 12 (Responsible Consumption and Production).
Recent publications highlight advancements in alginate degradation mechanisms, sucrose synthase engineering, and glycosyltransferase applications in biocatalytic routes for indigo/indican production. She supervises multiple PhD projects on enzyme optimization, machine learning for enzyme engineering, and sustainable bioprocessing.
Professional Activities: Peer review for journals like Nature Catalysis and Metabolic Engineering, conference organization, and editorial contributions. Active in promoting open-access science and sustainable biotechnology.
Labs/Teams: Leads the Enzyme Engineering and Structural Biology group at DTU, collaborating with industry and academic partners globally to advance biocatalytic solutions for environmental challenges.
