معرفی
Ditte Elisabeth Jæhger is a Consultant Lecturer at the Department of Health Technology, Technical University of Denmark (DTU). Her research focuses on cancer immunotherapy, particularly in developing innovative drug delivery systems and modulating tumor microenvironments to enhance adoptive T-cell therapies. She actively contributes to vaccine development, TLR agonist applications, and nanomedicine-based approaches for oncologic treatments.
Her recent publications emphasize sustained immune activation through combinatorial therapies, including TLR7/8 agonists, TGFβ inhibitors, and IL-12 surface-tethered T-cells. These works explore mechanisms like antigen spreading, macrophage polarization, and NK-dendritic cell interactions, aiming to improve anti-tumor efficacy. Her research also involves lipid nanoparticle vaccine platforms and in vivo tracking of immune cells using nanoparticle labeling systems.
As a former PhD student in the Liposome-based vaccines in cancer immunotherapy project (2016-2020), she collaborated with supervisors such as Dr. Thomas L. Andresen and Dr. Lise Roursgaard. She has presented at conferences on topics including copper-nanoparticle cell labeling and liposomal vaccination strategies.
