معرفی
Dr. Dirk W. Donker serves as Full Professor in Cardiovascular and Respiratory Physiology at the University of Twente, where he is deeply integrated with the interdisciplinary TechMed Centre. His academic leadership spans critical care physiology with specialized focus on extracorporeal life support systems and respiratory monitoring in intensive care settings.
Research interests prominently feature Extracorporeal Membrane Oxygenation (ECMO) applications, cardiogenic shock management, and neuro-ventilatory coupling in mechanically ventilated patients. His work bridges physiological modeling with clinical implementation, particularly in aging-related cardiovascular variability and advanced signal processing for non-invasive monitoring. Current investigations explore machine learning frameworks for blood pressure estimation and fluid responsiveness prediction in critical care.
Recent publication trends reveal intensive collaboration in multinational clinical trials like REMAP ECMO, with strong emphasis on adaptive trial design for left ventricular unloading. His 2025 output demonstrates methodological innovation through physiological-model-based neural networks and systematic reviews of ICU monitoring techniques, consistently targeting translational applications in extracorporeal life support.
Prof. Donker operates within the TechMed Centre ecosystem, which fosters engineering-medicine integration through cross-faculty initiatives. His collaborative network spans European critical care research groups, evidenced by co-authorship in major trials and systematic reviews addressing ECMO complications and hemodynamic monitoring challenges.


