معرفی
Diany Paola Calderon is an Associate Professor of Neuroscience at Weill Cornell Medical College, holding dual appointments in the Department of Anesthesiology and the Brain and Mind Research Institute. She was named the Nancy M. and Samuel C. Fleming Research Scholar in Intercampus Collaborations in 2021.
Her educational background includes an M.D. from Universidad el Bosque Medical School in Colombia (2000) and a Ph.D. from Albert Einstein College of Medicine of Yeshiva University (2010).
Dr. Calderon's research centers on neural mechanisms of consciousness and arousal, with emphasis on general anesthesia emergence, traumatic brain injury recovery, and sleep modulation. Her work bridges molecular neuroscience and clinical anesthesiology, investigating how basal forebrain circuits, brainstem nuclei, and circadian proteins regulate behavioral states. She employs rodent models with electrophysiological, behavioral, and biomarker approaches to study cognitive sequelae and neural network dynamics.
Analysis of her publications reveals a cohesive trajectory from fundamental arousal mechanisms (e.g., nucleus gigantocellularis function) to clinical applications in neurotrauma and anesthesia. Her work spans molecular signaling (cAMP pathways), cellular electrophysiology (burst firing patterns), and systems-level network dynamics (metastable states in consciousness recovery), demonstrating translational impact across neuroscience and critical care.
Her scientific recognition includes:
- Nancy M. and Samuel C. Fleming Research Scholar in Intercampus Collaborations (2021)
Dr. Calderon leads multiple NIH-funded initiatives as Principal Investigator, including an NSF project (2025-2026) developing NeuroTransitions for consciousness monitoring in clinical settings and an NINDS R01 (2023-2028) investigating cortical restoration mechanisms. She also contributes as Co-Investigator on NHLBI-funded hypertension research (2023-2026), demonstrating interdisciplinary collaboration across neurological and cardiovascular domains.
Based within Weill Cornell's Brain and Mind Research Institute and Anesthesiology Department, she integrates basic science with clinical applications through multidisciplinary teams focused on neural circuit mapping and therapeutic development for consciousness disorders.
