معرفی
Dr. Dianne McKay is a Professor of Immunology & Microbiology at Scripps Research, with a secondary affiliation at the Skaggs Graduate School of Chemical and Biological Sciences. She holds an M.D. from the University of Chicago (1983) and a B.S. from UC Berkeley (1978). Her research focuses on unraveling the immunologic mechanisms driving ischemia-induced kidney injury, particularly the role of innate immune responses in renal tubular epithelial cells during ischemia/reperfusion injury (IRI).
Her work employs ex vivo and in vivo models to study stress responses in human and murine renal cells, aiming to identify therapeutic targets for kidney protection during ischemic events. Key achievements include discoveries related to CD14 blockade for organ preservation and the role of DAMPs in immune activation. Dr. McKay has received notable awards such as the Baxter Healthcare Extramural Award (1994) and the Roche Organ Transplant Research Award (2000).
Her publications emphasize advancements in organ preservation techniques, molecular strategies from hibernation biology, and the interplay between innate immunity and ischemic injury. Current efforts prioritize translational research to improve outcomes for donated organs and patients undergoing kidney transplantation.
