Denys Khaperskyy

Dr. Denys Khaperskyy is an Associate Professor in the Department of Microbiology & Immunology at Dalhousie University (Faculty of Medicine). His research focuses on virus-host interactions, particularly influenza A virus and coronaviruses, exploring intrinsic cellular defenses and stress response mechanisms. He holds a BSc from National Taras Shevchenko University (Kyiv, Ukraine), a PhD from SUNY Buffalo, and completed postdoctoral training at Dalhousie University.

Research Interests
His lab investigates how viruses manipulate host stress responses (e.g., stress granules) and cellular defense mechanisms. Key areas include influenza A virus-induced host shutoff, coronaviruses’ inhibition of stress pathways, and antiviral strategies targeting viral proteins.

Recent Work Trends
Recent publications highlight influenza PA-X protein’s role in mRNA degradation, coronavirus Nsp1-mediated stress granule inhibition, and thiopurine antiviral effects on SARS-CoV-2 Spike proteins. Themes include viral immune evasion strategies and host-pathogen interactions.

Lab & Teaching
Teaches MICI 4114 (Advanced Virology) and MICI 3620 (Experiential Learning). Currently not recruiting graduate students.