معرفی
Craig McCormick is a Professor in the Department of Microbiology & Immunology at Dalhousie University’s Faculty of Medicine. He specializes in viral mechanisms and host defense systems, focusing on influenza, coronaviruses, and Kaposi’s sarcoma-associated herpesvirus (KSHV). His research explores how viruses manipulate stress responses, autophagy, and translational control to evade immune defenses.
Education:
- BSc from University of New Brunswick
- PhD from University of British Columbia
- Postdoctoral Training at University of California San Francisco
Research Interests: McCormick’s work integrates virology, immunology, and cell biology. Key areas include antiviral unfolded protein responses, viral inhibition of stress granules, and autophagy regulation in cancer and infectious diseases. He investigates how KSHV subverts cellular processes to promote oncogenesis and how influenza A virus disrupts host gene expression via proteins like PA-X. His studies also extend to antiviral drug development, leveraging insights from viral-host interactions.
Publications Trends: Recent work emphasizes coronaviruses (e.g., SARS-CoV-2 and HCoV-OC43), influenza A virus pathogenesis, and KSHV-induced cellular changes. His articles highlight novel antiviral strategies, such as thiopurines targeting coronavirus spike proteins and photodynamic inactivation methods for herpesviruses. Earlier studies explored the roles of viral proteins in mRNA stability and oncogene-induced senescence evasion.
Scientific Awards:
- Lecturer of the Year (2018)
- Rosemary Gill Award (2019)
- NS-CIHR RPP New Investigator Salary Award (2007–2012)
Advising & Grants: McCormick has led grants such as the NS-CIHR award and contributed to strategic training programs. His research collaborates with interdisciplinary teams, including work on synthetic metagenomics and zebrafish xenograft models for KSHV diseases.
Labs & Teams: Based in Dalhousie’s Department of Microbiology & Immunology, his lab focuses on viral stress responses and drug discovery. He co-founded the Canadian Society for Virology (2015) to foster virology research and education in Canada.
