Dennis Wilke

Dennis Wilke is a Researcher in the Resource Management Working Group at the Institute for Environmental Systems Research, University of Osnabrück. His research focuses on environmental systems science, neuroimaging of neurodevelopmental and neurodegenerative disorders, and the application of advanced MRI techniques to study brain structure-function relationships. He leads studies on autism spectrum disorder neurobiology, motor dysfunction mechanisms in dystonia/Parkinson's disease, and environmental enrichment interventions for repetitive behaviors.

• Expertise: Neuroimaging biomarkers | Cortico-basal ganglia circuits | Neuroplasticity mechanisms
• Active in mouse model development for movement disorders
• Key collaborator in transcallosal white matter research

Recent work emphasizes translational approaches linking genetic, environmental, and neuroimaging data to understand behavioral and motor impairments. His lab combines advanced diffusion MRI (free water imaging, NODDI), functional connectivity analysis, and behavioral phenotyping across species.