Dennis Goldfarb

Dennis Goldfarb is an Assistant Professor at Washington University School of Medicine, with dual appointments in the Department of Cell Biology & Physiology and the Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS). His research spans multiple DBBS tracks including Biochemistry, Biophysics, Structural Biology, and Computational & Systems Biology, while also contributing to the Center for Translational Bioinformatics and Siteman Cancer Center.

Research Interests:

• Computational mass spectrometry
• Proteomics
• High-performance computing pipelines
• Protein complex identification
• De novo peptide sequencing
• Biomedical data science

Recent Publication Trends

Dr. Goldfarb's recent work includes proteomic studies of histone ubiquitylation mechanisms, cell-cell junction complexity, and disease-related protein regulators, with applications in diabetes and neurodevelopmental disorders.

Labs & Collaborations

He leads the Goldfarb Lab, which develops open-source software for mass spectrometry. His team collaborates with institutions globally on projects spanning cancer biology, metabolic diseases, and virology.