Denis Kaynov

Denis Kaynov is a Professor at the Institute of Clinical and Molecular Medicine, NTNU, Norway. His research focuses on developing antiviral drug combinations targeting broad viral spectra and drug-resistant variants. He holds a PhD from the University of Helsinki (2005), followed by postdoctoral work at IGBMC (2005-2007) and CRP-Santé Luxembourg (2007-2009). His expertise spans virology, pharmacology, and immunology.

Key research interests include antiviral drug synergy, host-virus interactions in enteric infections, and translational therapeutics. Recent work emphasizes organoid models for studying viral diseases and testing antiviral cocktails. His lab explores JAK inhibitors’ role in viral propagation and investigates macrophage-augmented intestinal organoids for therapeutic screening.

Publications highlight drug combinations against enteroviruses, SARS-CoV-2 antibody responses, and repurposing FDA-approved drugs. He collaborates widely, mentoring students like Hilde Lysvand and Irene Trøen Frøysa. His work bridges basic research and clinical applications, addressing global viral threats with an emphasis on broad-spectrum solutions.