Debasis Mondal

Debasis Mondal is a Professor of Microbiology and Infectious Disease at Lipscomb University. His research focuses on cancer biology, HIV/AIDS pathogenesis, drug resistance mechanisms, and the therapeutic potential of natural compounds. He has pioneered studies on exosome biology, stem cell-based therapies, and synergistic drug combinations to combat prostate cancer and HIV. His work integrates molecular biology, pharmacology, and clinical applications.

Key areas of investigation include the regulation of androgen receptor (AR) and its splice variant AR-V7 in castration-resistant prostate cancer (CRPC), the role of exosomes in cancer progression and HIV latency, and the development of humanized mouse models for translational research. Dr. Mondal has contributed to understanding oxidative stress pathways in cancer and the neuroprotective effects of natural compounds like sulforaphane.

His publications highlight innovative approaches such as using focused ultrasound to enhance cancer drug efficacy and exploring osteopathic manipulative medicine's impact on neonatal care outcomes. Collaborative efforts with the NIH Extracellular RNA Communication Consortium aim to standardize exRNA research methodologies. Current projects include investigating circadian rhythm disruption's role in chemotherapy resistance and developing cyclotide-based antiviral therapies.

Dr. Mondal's work has been supported by grants focusing on translational medicine, with a strong emphasis on bridging basic science and clinical applications. He maintains an active research lab with a focus on interdisciplinary collaboration.