معرفی
Dean Nardelli is an Associate Professor in the Department of Biomedical Sciences within the College of Health Sciences at the University of Wisconsin-Milwaukee (UWM). He is actively engaged in research on Lyme borreliosis, with a focus on the immunological mechanisms underlying persistent arthritis following infection with Borrelia burgdorferi.
His research interests lie at the intersection of immunology and infectious disease, particularly in understanding how adaptive immune responses—specifically T cells—contribute to the development, progression, and resolution of Lyme arthritis. A central hypothesis in his work is that post-infectious autoimmunity may explain persistent symptoms in genetically predisposed individuals even after antibiotic treatment.
Dr. Nardelli leads research efforts in the Lyme Borreliosis Laboratory at UWM, where his team investigates both host and microbial factors influencing T cell differentiation and inflammatory outcomes in later-stage Lyme disease. His work aims to identify key immune pathways that could inform therapeutic strategies to reduce morbidity in affected patients.
While no publications or scientific awards are listed in the provided text, his research program emphasizes translational immunology and host response dynamics in tick-borne diseases. He also contributes to academic mentoring through various biomedical science degree programs at UWM, including BS, MS, and PhD levels across disciplines such as Diagnostic Imaging, Medical Laboratory Science, and Public Health Microbiology.
Dr. Nardelli's laboratory work integrates immunological analysis with clinical manifestations of infection, aiming to bridge mechanistic insights with patient outcomes in complex post-infectious syndromes.
