David L Glanzman

David L Glanzman serves as Professor in both the Department of Integrative Biology And Physiology and the Department of Neurobiology at the University of California Los Angeles. His research bridges molecular, cellular, and behavioral neuroscience with a primary focus on the fundamental mechanisms of learning and memory.

His research program investigates memory storage and synaptic plasticity using invertebrate models (particularly Aplysia californica) and zebrafish larvae. Key interests include:

• The role of nuclear mechanisms and epigenetic regulation in long-term memory storage
• Challenging the dominant synaptic plasticity hypothesis of memory
• RNA-mediated transfer of memory engrams
• Sensory processing and habituation mechanisms in developing organisms

His work has generated significant debate in neuroscience by questioning whether synaptic plasticity constitutes the primary mechanism for long-term memory storage.

Analysis of his recent publications reveals consistent focus on molecular mechanisms of memory across multiple model systems. His work increasingly incorporates zebrafish models for developmental neurotoxicology studies while maintaining his foundational research on Aplysia memory mechanisms. The publications demonstrate strong emphasis on epigenetic regulation, RNA involvement in memory storage, and the distinction between memory storage and expression mechanisms.

While no specific awards are listed in the provided text, his publication record in high-impact journals including eLife, Journal of Neuroscience, and Current Biology indicates significant recognition in the field.

Professor Glanzman's research program involves extensive collaboration across multiple laboratories, particularly evident in his zebrafish work which features large multi-author papers. His lab utilizes advanced techniques including in vivo confocal imaging, molecular manipulations, and detailed behavioral analysis to investigate memory mechanisms. Current research directions include examining environmental impacts on neurodevelopment and the fundamental question of where and how memories are stored at the molecular level.