David Krantz

David Krantz is a Professor at the David Geffen School of Medicine, University of California Los Angeles, with a dual appointment in the Department of Psychiatry and Biobehavioral Sciences. His career spans both clinical psychiatry and fundamental research using Drosophila genetics to explore neurotransmitter systems.

• Education: MD/PhD from UCLA (1991), Sc.B. in Neuroscience from Brown University (1983)

Research Interests focus on neurotransmitter transporters, neuromodulatory circuits, and environmental neurotoxicology. His work bridges Drosophila genetic models with translational psychiatry, particularly in disorders like major depressive disorder and obsessive-compulsive disorder.

Recent Publications highlight two major research threads: (1) rTMS clinical studies for psychiatric conditions, emphasizing biomarkers like pupillary reactivity and dosing regimens, and (2) Drosophila investigations into vesicular neurotransmitter transporters, octopamine receptors, and genetic responses to toxins such as ziram.

• Key Grants: NIH R01MH114017 (2018-2023), R21ES024113 (2016-2018), R01MH107390 (2015-2020), R01MH076900 (2007-2013), and T32ES015457 (2007-2026)

Lab Contributions include pioneering Drosophila models for Parkinson's disease-linked toxins, serotonin transporter mutations affecting behavior, and vesicular trafficking mechanisms. His clinical work integrates neurostimulation protocols with functional connectivity analysis and biomarker discovery.