معرفی
Professor David Hodgson serves as a Professor in the Department of Chemistry at Durham University, where his research group applies physical organic chemistry to solve biological and synthetic challenges with emphasis on nucleoside chemistry and bioconjugation techniques.
Research Focus: Hodgson's work centers on kinetic analysis and physicochemical properties to develop efficient synthetic methodologies. Key innovations include:
- Overcoming nucleoside solubility limitations through pH manipulation
- Designing moisture-stable pyrophosphate salts for nucleotide synthesis
- Creating anionic phosphorylation agents selective for aqueous bioconjugation
- Engineering protocols for nucleic acid and polysaccharide modification
His publication trajectory (2025-2016) reveals expanding applications from fundamental kinetics to carbon dioxide-protein interactions and biological system engineering, demonstrating consistent methodological innovation in physical organic chemistry.
Professor Hodgson actively supervises doctoral researchers Alex Greer, Victoria Liu, Lauren Billett, Matthew Waterson, and Willow Baxter. His laboratory maintains integrated projects in nucleotide analog synthesis, enzyme kinetics, and polysaccharide functionalization, translating mechanistic insights into practical synthetic solutions for chemical biology applications.
