معرفی
Professor David Greensmith serves as Professor of Cardiac Physiology and Associate Dean for International Development at The University of Salford's School of Science, Engineering & Environment. He is an active researcher, educator, and leader in cardiovascular science with significant contributions to understanding cardiac physiology, inflammatory cardiovascular disease, and drug-induced cardiotoxicity.
Greensmith earned his undergraduate degree in Biological Sciences from The University of Salford in 2005, followed by a PhD and two post-doctoral positions in cardiac physiology at The University of Manchester under Professors David Eisner, Mahesh Nirmalan and Andrew Trafford. He returned to Salford in 2014 as a lecturer in Biomedical Science and has since risen to his current professorship.
His research focuses on the cellular basis of normal and dysfunctional heart function, with particular emphasis on calcium signaling and oxidative stress mechanisms. Current projects investigate why anti-cancer drugs cause heart failure and how abnormal heart cell function contributes to coronary artery disease. His lab also explores natural product derivatives for cancer treatment, particularly against medulloblastoma and leukemia.
Greensmith's recent publications demonstrate his dual focus on cardiac physiology and cancer therapeutics, with significant work on cytokines in coronary artery disease, calcium signaling mechanisms, and natural compounds like Tripterygium wilfordii derivatives. His research spans basic physiological mechanisms to potential clinical applications.
- The Physiological Society's Otto Hutter Teaching Prize (2023)
- Associate Editor for Current Research in Physiology
- President of the British Society for Cardiovascular Research (starting January 2025)
- Scientific Director of KidsCan (starting January 2025)
- Physiological Society representative for The University of Salford (since 2017)
As an educator, Greensmith has led physiology modules and the Human Biology & Infectious Diseases degree programme. He co-leads initiatives to enhance widening participation in research careers, particularly for students from disadvantaged socioeconomic backgrounds. His 2023 Otto Hutter Teaching Prize recognized his excellence in physiology education. He accepts self-funded PhD students interested in cardiac physiology, drug-induced cardiotoxicity, and natural product-based cancer therapeutics.
