معرفی
David Gidalevitz is an Associate Professor of Physics at the Lewis College of Science and Letters, Illinois Institute of Technology. His research bridges biophysics and materials science, focusing on molecular structures at soft interfaces, particularly lipid membranes and their interactions with peptides and proteins.
- Education: Diplom, Engineering Physics (Urals Federal University, 1988)
- PhD, Chemistry, Materials and Interfaces (Weizmann Institute, 1996)
His work utilizes synchrotron X-ray scattering techniques to investigate:
- Structure-function relationships in pulmonary surfactant films
- Antimicrobial peptide-membrane interactions
- Peptidomimetics for cancer therapy
- Lipid-cholesterol dynamics in biological membranes
Recent publications highlight his lab's discoveries on cholesterol's role in membrane stability, the dual mechanism of OAK peptidomimetics in cancer cells, and structural adaptations in bacterial membranes conferring antibiotic resistance. His team employs advanced methods including X-ray reflectivity, GIXD, GIXOS, and Langmuir isotherms.
Notable projects include:
- Structure and function of natural pulmonary surfactants
- Host defense peptidomimetics targeting cancer cells
- Next-generation antibiotics via antimicrobial peptides
