David D Dean

Dr. David D Dean is a Research Professor in the Department of Comprehensive Dentistry at the University of Texas Health Science Center at San Antonio. His research focuses on biomaterial-tissue interactions, stem cell biology, and regenerative medicine, with an emphasis on aging-related skeletal and salivary gland regeneration. He holds a B.S. and Ph.D., though specific degree institutions are not detailed in the provided text.

Research Interests:

• Interaction of osteoblasts with titanium implants and prostaglandin modulation.
• Characterization of wear debris particles and their effects on bone cell behavior.
• Tissue engineering scaffolds for battlefield bone repair via collaborations with UTSA, Carnegie Mellon, and the Institute for Surgical Research.

His recent work emphasizes extracellular matrix (ECM) roles in stem cell niches, aging-related tissue decline, and salivary gland regeneration. Articles highlight breakthroughs in rejuvenating aged mesenchymal stem cells using ECM-based therapies and understanding Cyr61/CCN1’s role in bone marrow niche preservation.

Professional Collaborations: Active partnerships with UTSA, Carnegie Mellon University, and the Brooke Army Medical Center.