Davide Cinat

Davide Cinat is a researcher at the University of Groningen specializing in salivary gland biology, organoid development, and radiation effects on stem cells. His work primarily focuses on understanding how radiation damages tissues and how regeneration can be promoted through stem cell mechanisms.

His research interests span several interconnected fields:

• Salivary gland organoid development and function
• Stem cell response to radiation damage
• Mechanisms of tissue regeneration after radiation therapy
• Mitophagy and cellular senescence in irradiated tissues
• Comparative effects of proton versus photon radiation therapy

Davide's publication record demonstrates a strong focus on understanding the molecular mechanisms underlying radiation damage and tissue regeneration, with particular emphasis on salivary gland function. His research combines organoid technology with radiation biology to develop potential therapeutic approaches for radiation-induced tissue damage, showing significant promise in improving outcomes for cancer patients undergoing radiotherapy.

His notable contributions include work on mitophagy induction to improve stem cell function after irradiation and investigations into how proton therapy affects neuroimmune responses, with his 2021 review article on DNA damage and stem cell response accumulating 58 citations.

Davide has established a productive collaboration with researchers including R.P. Coppes and L. Barazzuol, forming a research group that has produced multiple high-impact publications in Radiotherapy and Oncology and Frontiers in Cell and Developmental Biology.