معرفی
David Curtis is Associate Professor and Head of the Division of Blood Cancer Research at the Australian Centre for Blood Diseases, Monash University, and Alfred Health. He is an NHMRC Senior Research Fellow B and an active clinical haematologist and bone marrow transplant physician. His research focuses on the genetic and epigenetic regulation of normal and leukemic stem cells using mouse models.
- Department: Department of Haematology
- School: Faculty of Medicine
- University: Monash University
- Clinical Affiliation: Alfred Health
David Curtis completed his clinical training in Clinical Haematology and Bone Marrow Transplantation at the University of Melbourne in 1994. He held a NHMRC postgraduate scholarship at the Walter and Eliza Hall Institute (1994–1997) and a NHMRC CJ Martin Fellowship at the NIH (1998–2001) under Dr. David Bodine, studying HMGB3 in hematopoietic stem cells.
- 1994: Clinical Haematologist and Bone Marrow Transplant Physician, University of Melbourne
- 1994–1997: NHMRC Postgraduate Scholar, WEHI
- 1998–2001: NHMRC CJ Martin Fellow, NIH
His research interests include identifying improved therapies for acute leukemia through mouse models of hematopoietic stem cells. He uses ENU-mutagenesis to discover hematopoiesis-regulating genes. Key areas include T-cell ALL driven by bHLH complexes, oncogene-induced apoptosis in myelodysplasia, epigenetic changes in AML/MDS, and PRMT5 inhibitors. His work contributes to UN Sustainable Development Goals in health and well-being.
The most recent publications show a strong focus on clinical translation, stem cell transplantation, leukemia mechanisms, and targeted therapies. Trends include post-transplant interventions, chemoresistance, donor chimerism, and antiviral strategies in immunocompromised patients.
Dr. Curtis has received several prestigious awards and fellowships:
- NHMRC Senior Research Fellow B
- Charles and Sylvia Viertel Senior Research Fellowship
- Honorary NHMRC Practitioner Fellowship
- Victorian Cancer Agency Fellowship
- NHMRC Postgraduate Scholarship
- NHMRC CJ Martin Fellowship
He has served as Primary Chief Investigator on multiple national and international research projects, including clinical trials on venetoclax, JNJ-53718678 for RSV, and platform trials like INTERCEPT. He has reviewed NHMRC grants since 2005 and served on advisory panels for the Leukemia Foundation and NSW Cancer Council. He has also been on the editorial board of Stem Cells since 2007 and has been an invited speaker at major hematology conferences.
Dr. Curtis leads the Division of Blood Cancer Research at the Australian Centre for Blood Diseases, Monash University. His team integrates basic science with clinical translation, focusing on stem cell biology, leukemia, and transplantation outcomes. Collaborations include Murdoch Children's Research Institute, Burnet Institute, and international networks.
