David C. Page

David C. Page is a Professor of Biology at the Massachusetts Institute of Technology (MIT) and a Core Member of the Whitehead Institute for Biomedical Research. He is also an Investigator at the Howard Hughes Medical Institute (HHMI). His research focuses on genetic differences between sexes, including their implications for health, disease, and evolution. Page holds an MD from Harvard Medical School (1984) and a BS in Chemistry from Swarthmore College (1978).

Research Interests

Page’s work spans three primary areas: sex differences in health and disease, sex chromosome genomics, and germ cell origins and development. His lab uses comparative biology, evolutionary analysis, and clinical approaches to study how genetic variations between males and females influence medical outcomes beyond reproductive systems.

Key Awards

• Howard Hughes Medical Institute Investigator (1990)
• MacArthur Fellowship (1986)
• Member, National Academy of Sciences (2005)
• Member, National Academy of Medicine (2008)

Recent Research Trends

Recent work highlights the role of inactive X and Y chromosomes in modulating autosomal gene expression, sex-specific gene expression patterns, and epigenetic influences on cancer susceptibility. His publications emphasize the interplay between chromosomal biology and human disease mechanisms.

Lab and Collaborations

Page’s lab at the Whitehead Institute integrates experimental and computational approaches to study sex chromosome biology. Collaborations include the Howard Hughes Medical Institute and numerous institutions, focusing on translational research in genetics and medicine.