Daniela James

Daniela James is an Assistant Research Professor in the Department of Biochemistry and Molecular Biology at Pennsylvania State University, affiliated with the Mahony Lab. Her research focuses on genomics, epigenetics, and transcription factor analysis, with applications in cancer research and molecular biology. She holds a PhD in genetics, as evidenced by her 2016 dissertation on yeast chromosome segregation.

Her work spans diverse topics, including regulatory element analysis using computational tools, antibody validation for transcription factors, and estrogen receptor-mediated apoptosis in breast cancer. Recent contributions include developing methods for multimapped read allocation and analyzing chromatin dynamics via neural networks. Earlier studies explored cell cycle regulation in fission yeast and ribosomal DNA dynamics.

Dr. James has contributed to high-throughput screening of antibodies (2021) and explored structure-function relationships of estrogenic compounds in cancer (2020). Her lab’s research integrates bioinformatics, molecular biology, and pharmacology to address fundamental biological questions with clinical relevance.

No scientific awards are explicitly mentioned. She advises students in her lab but no formal advisee list is provided. Her work is supported by grants focused on genomic technologies and cancer biology. The Mahony Lab serves as her primary research hub, collaborating on projects involving chromatin accessibility and transcription factor dynamics.