معرفی
Daniel Oprian is the Louis and Bessie Rosenfield Professor of Biochemistry at Brandeis University, with affiliations in the Neuroscience Program and the Benjamin and Mae Volen National Center for Complex Systems. His research focuses on the structure-function relationships of G protein-coupled receptors, particularly visual pigments.
- University: Brandeis University
- Department: Department of Biochemistry
- Affiliated institutions: Neuroscience Program, Volen Center
Research Interests:
Dr. Oprian's lab investigates spectral tuning mechanisms in human visual pigments, molecular bases of retinal diseases like retinitis pigmentosa, and structural analysis of GPCR activation states. They employ techniques spanning biochemistry, mutagenesis, transgenic animal models, and X-ray crystallography.
Recent Research Trends:
His publications highlight work on terpene synthases, retinal disease mechanisms, and structural characterization of GPCR complexes. Studies span enzyme catalysis, calcium signaling, and nanoscale membrane systems.
Scientific Awards:
- Louis and Bessie Rosenfield Professorship in Biochemistry
Education:
Ph.D., M.S., and B.S. from the University of Michigan-Ann Arbor.
Laboratory:
The Oprian Lab at Brandeis explores GPCR structure-function relationships, focusing on rhodopsin activation mechanisms and retinal diseases. Their work bridges classical biochemistry with advanced structural and electrophysiological approaches.
