Daniel Lacorazza

Daniel Lacorazza, Ph.D. is a Professor in the Department of Pathology & Immunology at Baylor College of Medicine and leads the Experimental Immunology & Hematology Laboratory at Texas Children’s Hospital. His research focuses on genetic and epigenetic mechanisms in normal and leukemic blood cell regulation.

• Education: MSc and PhD from University of Buenos Aires; postdoctoral training at NIH and Memorial Sloan-Kettering.

Research Interests: Elucidating how transcription factors like KLF4 and ELF4 regulate hematopoietic stem cell self-renewal and leukemia progression, with a focus on context-dependent oncogenic/ tumor-suppressive roles.

Publication Trends: Recent work explores KLF4-DYRK2 pathways in CML, MAP2K7 inhibitors for T-ALL, and epigenetic vulnerabilities in leukemia stem cells using mouse models.

• Scientific Awards: Alkek Award in Experimental Therapeutics.

Advising & Grants: Mentors graduate and postdoctoral researchers. Receives funding from NCI, NIAID, CPRIT, DARPA, and Baylor institutions.

Labs & Teams: Collaborates with Baylor’s Center for Drug Discovery and Northwestern University medicinal chemists on precision therapies.