معرفی
Dr. Daniel Herschlag is a Professor of Biochemistry at Stanford University, with a courtesy appointment in Chemical Engineering. He leads the Herschlag Lab, which investigates fundamental RNA and protein behavior using interdisciplinary approaches integrating physics, chemistry, and biology. The lab pioneers high-throughput quantitative methods to study enzymatic catalysis, RNA folding, and molecular interactions.
- Research Interests:
- Enzyme mechanisms and catalysis
- RNA structure and dynamics
- Protein-RNA recognition
- Evolution of molecular interactions
- Quantitative Cellular Biochemistry (QCB)
Recent publications highlight innovations like SEISMICgraph for RNA structure visualization, SPARKfold for protein unfolding kinetics, and ensemble modeling of serine proteases. These studies advance understanding of molecular conformational landscapes and their impact on biological function.
- Scientific Honors:
- Member, National Academy of Sciences (2018)
- Member, American Academy of Arts and Sciences (2023)
- Stein and Moore Award (2022)
- Founders Award, Biophysical Society (2020)
- Advising & Collaborations:
- Doctoral Dissertation Advisor for Siyuan Du, John Shin, and Gabriel Tauber
- Postdoctoral sponsorships for Patrick Almhjell, Albert Lee, and Jimin Yoon
- Key collaborations with Fordyce Lab and Al-Hashimi Lab
The lab's work bridges foundational research with applications in biomedical engineering and industrial enzyme design, supported by programs in Stanford's Biochemistry and Biophysics PhD curricula.
