معرفی
Dr. Damien D. Pearse is a Professor of Neurological Surgery whose research focuses on autologous cell therapies and extracellular vesicles for nervous system repair. His work spans both peripheral and central nervous system injuries, with clinical translation of Schwann cell therapies for spinal cord injury.
- Enhanced Schwann cell therapies through combinatorial strategies
- Extracellular vesicle-based diagnostics and therapeutics
- Post-translational protein modifications in neural injury
- Development of smart biomaterials for neural repair
His research explores:
- ATE1/arginylation mechanisms in CNS damage
- TG2's role in neurological diseases
- Cyclic AMP-mitogen signaling cross-targeting
Publications reveal a focus on neurotrauma (2025), sex-specific immune responses (2024), and transglutaminase biology in multiple sclerosis (2022). Current work emphasizes clinical translation of cell therapies and biomaterials integration.
Laboratory investigations include:
- Neuronal cell death pathways
- Exosome-mediated neuroprotection
- Signal transduction in regeneration
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