
Dale L. Boger
استاد · Synthetic Organic Chemistry
Irell and Manella Graduate School of Biological Sciencesمعرفی
Dale L. Boger is a Professor of Chemistry at The Scripps Research Institute (TSRI), where he leads the Boger Group specializing in synthetic organic and medicinal chemistry. His academic roles include serving as co-Chair (2017-2018) and Chairman (2013-2017) of the Chemistry Department. Boger earned his B.S. from the University of Kansas (1975) and Ph.D. from Harvard University (1980). His research focuses on total synthesis of natural products, development of synthetic methodologies, and antibiotic design, particularly addressing antibiotic resistance via glycopeptide analogs like vancomycin.
Key honors include the Paul Janssen Prize (2002), RSC Robert Robinson Award (2017), and election to the National Academy of Sciences (2014). His work spans collaborations in bioorganic chemistry, molecular modeling, and drug design. The Boger Group’s lab includes numerous students and postdocs, advancing projects such as maxamycins and guanidine-modified vancomycins. Funding includes NIH grants and industry partnerships, highlighting his contributions to both academic and applied research.
Research highlights include groundbreaking studies on vancomycin analogs with dual mechanisms of action to combat resistance, as well as contributions to TLR agonists and neurovascular drug delivery. His legacy includes over 300 publications and impactful patents in antibiotic design and synthetic organic chemistry.
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