Dagna Lorenzo

Dr. Dagna Lorenzo is an Associate Professor of Internal Medicine at Vita-Salute San Raffaele University School of Medicine in Milan, Italy, and Head of the Unit of Immunology, Rheumatology, Allergy, and Rare Diseases at IRCCS San Raffaele Scientific Institute. She holds leadership roles including Coordinator of the Clinical Immunology and Rheumatology Unit and Co-Director of the European School of Internal Medicine (ESIM). Her expertise spans over 25 years in clinical and translational research, with a focus on autoimmune/autoinflammatory diseases, immunotherapy, and the interplay between infections and immunity.

Education: Medical Doctor (MD) summa cum laude from Università degli Studi di Milano; Board Certified in Internal Medicine from Vita-Salute San Raffaele University.

Research Interests: Pathogenesis and treatment of autoimmune/autoinflammatory diseases, immune-related adverse effects of cancer immunotherapy, Erdheim-Chester disease mechanisms, herpesvirus-induced vasculitides, γδ T lymphocyte function, and apoptosis pathways in autoimmune lymphoproliferative syndrome.

Publications (432+ articles): Recent work focuses on VEXAS syndrome (clonal dominance mechanisms), systemic sclerosis complications, and novel therapies for giant cell arteritis and Takayasu arteritis. Highlights include studies on FDG-PET imaging for vasculitis prognosis and Doppler ultrasound for mesenteric ischemia assessment.

Awards: Fellow of the American College of Physicians (ACP), Honorary Fellow of the European Federation of Internal Medicine (EFIM).

Grants & Teams: Leads multidisciplinary teams in rare diseases and chairs the EFIM Rare Disease Working Group. Collaborates internationally on initiatives like the Erdheim-Chester Global Alliance and the National Board of Medical Examiners (NBME).

Labs/Teams: Directs the Immunology Unit at San Raffaele Scientific Institute, focusing on translational research bridging clinical practice and molecular mechanisms.